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Article in English | AIM | ID: biblio-1270705

ABSTRACT

Acinetobacter baumannii is an important cause of hospital-acquired infections. The occurrence of carbapenem resistance that is caused by the carbapenem-hydrolysing class D ?-lactamases and the metallo-?-lactamases (MBLs) limits the range of therapeutic alternatives in treating A. baumannii infections. In this study; two multiplex polymerase chain reactions were performed to screen for both carbapenem-hydrolysing class D ?-lactamases and MBL genes in 97 clinical isolates of A. baumannii. Oxacillinase (OXA)-51 had a prevalence of 83 (81/97); and OXA-23 had a prevalence of 59 (57/97). One isolate was positive for an MBL [Verona integron-encoded metallo ?-lactamases (VIM)]. Therefore; continuous surveillance and monitoring of A. baumannii is crucial because of the high prevalence of antibiotic resistance genes


Subject(s)
Acinetobacter baumannii , Carbapenems , Cross Infection , Drug Resistance , Prevalence
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